# GlioState analysis: cross-platform replication of Neftel-style state calls (draft)
## Data (not redistributed; re-download)
- GEO GSE131928 (Neftel et al., Cell 2019; PMID 31327527): GSM3828672 Smart-seq2 TPM (7,930 cells), GSM3828673 10X (16,201 cells), cell->tumor metadata xlsx. Processed data only (authors state raw data not in GEO). GEO data are public; check the GEO/authors' terms of use before reuse.
- Signatures: third-party transcription of the Neftel meta-modules, https://github.com/ahd44/scrna_seq_glioblastoma/blob/main/metamodule_genesets.csv (no licence file; NOT verified against the paper's Table S2 — the official supplement could not be downloaded without bypassing a download interstitial). Sanity check: all marker genes quoted in the paper text (e.g. GFAP, S100B, OLIG1, PLP1, SOX4, DCX, VIM, HILPDA) are present in the expected modules. AC module has 39 genes, others 50.
## Notes
- Labels are the signature-score calls, not ground truth. No CNV-based malignant-cell identification.

> The analysis script and the discarded first run are not published on this site.