{"id":"VC0004","type":"paper","title":"AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.","authors_or_org":"Ma C, Zhang H, Rao Y, Jiang X, Liu B, Sun Z, Song Z, Gao Y, Cui Y, Liu X, Li Z.","date":"2025-12-11","year":"2025","venue":"NPJ digital medicine","url":"https://doi.org/10.1038/s41746-025-02198-6","doi":"10.1038/s41746-025-02198-6","pmid":"41381900","brain_tumor_focus":"no","tags":["review","preclinical","validation"],"tag_slugs":["review","preclinical","benchmark"],"tag_labels":["Review","Preclinical","Benchmark & validation"],"tag_labels_zh":["综述","临床前","基准评测与验证"],"unmapped_tags":[],"one_line_summary_en":"Review of AI virtual cell models in preclinical research: technical pathways and validation.","one_line_summary_zh":"综述：AI虚拟细胞在临床前研究中的技术路径与验证机制。","verified":"yes","verification_source":"Europe PMC","page_url":"https://gliostate.com/library/VC0004/","api_url":"https://gliostate.com/api/items/VC0004.json","sameAs":["https://doi.org/10.1038/s41746-025-02198-6","https://pubmed.ncbi.nlm.nih.gov/41381900/"],"is_preprint":false,"facets":{"type":"https://gliostate.com/library/type/paper/","year":"https://gliostate.com/library/year/2025/","tags":["https://gliostate.com/library/tag/review/","https://gliostate.com/library/tag/preclinical/","https://gliostate.com/library/tag/benchmark/"]},"cited_by":[],"related":[{"id":"VC0133","title":"Anatomically aware simulation of patient-specific glioblastoma xenografts","shared_tags":["preclinical"],"page_url":"https://gliostate.com/library/VC0133/","api_url":"https://gliostate.com/api/items/VC0133.json"},{"id":"VC0070","title":"In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma.","shared_tags":["preclinical"],"page_url":"https://gliostate.com/library/VC0070/","api_url":"https://gliostate.com/api/items/VC0070.json"},{"id":"VC0006","title":"Beyond the drug-centric view: Advancing AI virtual cell platforms for environmental perturbation modelling.","shared_tags":["review"],"page_url":"https://gliostate.com/library/VC0006/","api_url":"https://gliostate.com/api/items/VC0006.json"},{"id":"VC0084","title":"Current landscape of single-cell genomics in meningioma.","shared_tags":["review"],"page_url":"https://gliostate.com/library/VC0084/","api_url":"https://gliostate.com/api/items/VC0084.json"},{"id":"VC0007","title":"Can AI build a virtual cell? Scientists race to model life's smallest unit.","shared_tags":["review"],"page_url":"https://gliostate.com/library/VC0007/","api_url":"https://gliostate.com/api/items/VC0007.json"},{"id":"VC0058","title":"Virtual Cell Challenge 2026: Benchmarking zero-shot generalization across cellular contexts.","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0058/","api_url":"https://gliostate.com/api/items/VC0058.json"}]}