Core2Edge: a human glioblastoma organoid-brain slice model capturing infiltration and transcriptional heterogeneity from core to single-cell dispersion.
Core2Edge: GBM organoid-brain slice infiltration model (Nat Protoc).Core2Edge:GBM类器官-脑片浸润模型。
DELPHAI: AI agent for sc perturbation prediction + LLM mechanism on GBM organoids with TMZ; OT+PCA beat baselines.DELPHAI:GBM类器官+TMZ的单细胞扰动预测与LLM机制解读;最优传输+PCA优于基线。
AetherCell unifies clinical RNA-seq and perturbation assays for generative response prediction and in vivo repurposing.AetherCell统一临床RNA-seq与扰动实验流形,做生成式响应预测并支持体内药物重定位。
Patient-specific GBM xenograft growth/invasion model on mouse brain anatomy; ABC fit; treatment via parameter perturbation.基于小鼠脑解剖的患者特异性GBM异种移植生长/侵袭模型;ABC拟合;通过扰动参数模拟治疗。