Keystone: Single Cell Biology: Expanding Potential Across Diseases
Keystone Symposia · Banff, Canada (to Feb 18) · 2027-02-15
Keystone 2027 single-cell/spatial/perturbation meeting.
Tag: scRNA-seq
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Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations
Suter et al. · Nature Communications · 2026-01-07
scFOCAL/ISOSCELES links GBM cell states to L1000 signatures; predicts state-specific sensitivity and OLIG2i+Depatux-M combo.
Single-cell analysis reveals a longitudinal trajectory of meningioma evolution and heterogeneity.
Lee JY, Lee EJ, Seo BY, Kim J, Song Y, Lee D, Moon N, Koo H, Park CK, Kim MS, Park SI, Nam DH, Kong DS, Sa JK. · Nature communications · 2025-07-01
Longitudinal single-cell trajectory of meningioma evolution.
Large-scale foundation model on single-cell transcriptomics.
Hao M, Gong J, Zeng X, Liu C, Guo Y, Cheng X, Wang T, Ma J, Zhang X, Song L. · Nature methods · 2024-06-06
scFoundation: 100M-parameter model on ~50M human cells (Tsinghua/BioMap).
scGPT: toward building a foundation model for single-cell multi-omics using generative AI.
Cui H, Wang C, Maan H, Pang K, Luo F, Duan N, Wang B. · Nature methods · 2024-02-26
scGPT: generative pretrained transformer on 33M cells (Bo Wang lab).
Single-cell transcriptomic analyses provide insights into the cellular origins and drivers of brain metastasis from lung adenocarcinoma.
Wang Z, Wang Y, Chang M, Wang Y, Liu P, Wu J, Wang G, Tang X, Hui X, Liu P, Guo X, Xing B, Wang Y, Han Z, Ma W. · Neuro-oncology · 2023-07-01
Cellular origins and drivers of brain metastasis by scRNA-seq.
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.
Liu I et al. · Nature genetics · 2022-12-05
Liu et al.: tumor cell states and spatial organization of H3-K27M DMG across ages.
Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response.
Wang AZ et al. · Genome medicine · 2022-05-10
Single-cell profiling of human dura and meningioma.
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Zhang L et al. · Cancer cell · 2019-08-29
Vladoiu et al.: medulloblastoma progenitors & developmental origins.
Resolving medulloblastoma cellular architecture by single-cell genomics.
Hovestadt V et al. · Nature · 2019-07-24
Hovestadt et al.: medulloblastoma cellular architecture by single-cell genomics.
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
Neftel C et al. · Cell · 2019-07-18
Neftel et al.: four GBM malignant states (NPC/OPC/AC/MES), plasticity and genetics.
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.
Filbin MG et al. · Science (New York, N.Y.) · 2018-04-01
Filbin et al.: OPC-like programs in H3K27M gliomas.
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.
Venteicher AS et al. · Science (New York, N.Y.) · 2017-03-01
Venteicher et al.: IDH-mutant glioma lineages and microenvironment by scRNA-seq.