DELPHAI, AI Agent for Predicting Drug Response and Resistance
Peng et al. · preprint · 2025-09-17
DELPHAI: AI agent for sc perturbation prediction + LLM mechanism on GBM organoids with TMZ; OT+PCA beat baselines.
Tag: Therapy
3 items, newest first.
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Multiscale mathematical model-informed reinforcement learning optimizes combination treatment scheduling in glioblastoma evolution.
Liu Z, Zhang J, Hong L, Nie Q, Sun X. · Science advances · 2025-08-08
Multiscale mechanistic model + reinforcement learning to optimize glioma combination scheduling.
A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets.
Wang L, Jung J, Babikir H, Shamardani K, Jain S, Feng X, Gupta N, Rosi S, Chang S, Raleigh D, Solomon D, Phillips JJ, Diaz AA. · Nature cancer · 2022-12-20
Single-cell atlas of GBM evolution under therapy.