Virtual Cell Challenge 2026: Benchmarking zero-shot generalization across cellular contexts.
Arc Virtual Cell Initiative Team, Goodarzi H. · Cell · 2026-08-26
2026挑战赛论文：跨细胞情境零样本泛化基准。
标签：基准评测与验证
共 12 条，按时间倒序。
An Empirical Comparison of Virtual Cell Models: Perturbation Prediction, Representation, and the Baseline Gap
Denvis O. · Research Square · 2026-07-22
虚拟细胞模型实证比较：与基线差距依旧。
Signal, Bounds, and Baselines: Principles for Evaluating Virtual Cell Perturbation Models
Vollenweider M, Bühlmann P. · bioRxiv · 2026-04-22
虚拟细胞扰动模型评估原则：信号、上界与基线。
scPRINT-2: Towards the next-generation of cell foundation models and benchmarks
Kalfon J, Peyré G, Cantini L. · bioRxiv · 2025-12-15
scPRINT-2：新一代细胞基础模型与基准。
AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.
Ma C, Zhang H, Rao Y, Jiang X, Liu B, Sun Z, Song Z, Gao Y, Cui Y, Liu X, Li Z. · NPJ digital medicine · 2025-12-11
综述：AI虚拟细胞在临床前研究中的技术路径与验证机制。
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation.
Viñas Torné R, Wiatrak M, Piran Z, Fan S, Jiang L, Teichmann SA, Nitzan M, Brbić M. · Nature biotechnology · 2025-08-25
Systema：剔除系统性变异后评估扰动预测。
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines.
Ahlmann-Eltze C, Huber W, Anders S. · Nature methods · 2025-08-04
Ahlmann-Eltze等：深度模型未超越简单线性基线。
Multimodal Benchmarking of Foundation Model Representations for Cellular Perturbation Response Prediction
Hasanaj E, Cole E, Mohammadi S, Addagudi S, Zhang X, Song L, Xing EP. · bioRxiv · 2025-06-28
多模态基础模型表示的扰动预测基准。
Virtual Cell Challenge: Toward a Turing test for the virtual cell.
Roohani YH et al. · Cell · 2025-06-01
Arc研究所发起虚拟细胞挑战赛，作为虚拟细胞的“图灵测试”。
Benchmarking foundation cell models for post-perturbation RNA-seq prediction.
Csendes G, Sanz G, Szalay KZ, Szalai B. · BMC genomics · 2025-04-23
Csendes等：基础模型扰动预测不如简单基线。
Zero-shot evaluation reveals limitations of single-cell foundation models.
Kedzierska KZ, Crawford L, Amini AP, Lu AX. · Genome biology · 2025-04-18
Kedzierska等：零样本评估揭示单细胞基础模型局限。
PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction
Wenteler A, Occhetta M, Branson N, Curean V, Huebner M, Dee W, Connell W, Chung SP, Hawkins-Hooker A, Ektefaie Y, Valdez Córdova CM, Gallagher-Syed A. · bioRxiv · 2024-10-03
PertEval-scFM：扰动预测基准。