Scaling Dense Representations for Single Cell with Transcriptome-Scale Context
Ho N, Ellington CN, Hou J, Addagudi S, Mo S, Tao T, Li D, Zhuang Y, Wang H, Cheng X, Song L, Xing EP. · bioRxiv · 2024-12-03
GenBio AI的AIDO.Cell：全转录组上下文的稠密单细胞模型。
年份：2024
共 13 条，按时间倒序。
How to build the virtual cell with artificial intelligence: Priorities and opportunities.
Bunne C et al. · Cell · 2024-12-01
奠基性综述：提出“AI虚拟细胞”定义与多尺度、多模态路线图。
A method for in silico exploration of potential glioblastoma multiforme attractors using single-cell RNA sequencing.
Vieira Junior MG, de Almeida Côrtes AM, Gonçalves Carneiro FR, Carels N, Silva FABD. · Scientific reports · 2024-10-29
基于单细胞数据的GBM吸引子计算探索。
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model.
Yang X et al. · Cell research · 2024-10-08
GeneCompass：知识引导的跨物种基础模型（中科院）。
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma.
Liu SJ et al. · Genome biology · 2024-10-07
GBM体内Perturb-seq：解析驱动基因与放疗反应——脑肿瘤虚拟细胞的关键训练数据类型。
PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction
Wenteler A, Occhetta M, Branson N, Curean V, Huebner M, Dee W, Connell W, Chung SP, Hawkins-Hooker A, Ektefaie Y, Valdez Córdova CM, Gallagher-Syed A. · bioRxiv · 2024-10-03
PertEval-scFM：扰动预测基准。
Large-scale foundation model on single-cell transcriptomics.
Hao M, Gong J, Zeng X, Liu C, Guo Y, Cheng X, Wang T, Ma J, Zhang X, Song L. · Nature methods · 2024-06-06
scFoundation：清华/百图生科的1亿参数单细胞基础模型。
Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival.
Haley MJ et al. · Science advances · 2024-05-17
缺氧协调GBM髓系细胞空间格局。
Integrative spatial analysis reveals a multi-layered organization of glioblastoma.
Greenwald AC et al. · Cell · 2024-04-22
Greenwald等：GBM多层次空间组织。
Towards a general-purpose foundation model for computational pathology.
Chen RJ et al. · Nature medicine · 2024-03-19
UNI：通用病理基础模型（含脑肿瘤分型任务）。
scGPT: toward building a foundation model for single-cell multi-omics using generative AI.
Cui H, Wang C, Maan H, Pang K, Luo F, Duan N, Wang B. · Nature methods · 2024-02-26
scGPT：基于3300万细胞的生成式单细胞基础模型（王波团队）。
A simple agent-based hybrid model to simulate the biophysics of glioblastoma multiforme cells and the concomitant evolution of the oxygen field.
Saucedo-Mora L, Sanz MÁ, Montáns FJ, Benítez JM. · Computer methods and programs in biomedicine · 2024-01-26
GBM细胞生物物理主体模型。
Disentanglement of single-cell data with biolord.
Piran Z, Cohen N, Hoshen Y, Nitzan M. · Nature biotechnology · 2024-01-15
biolord：解耦表示进行反事实细胞预测。